Patients with uterine fibroids 5cm and larger in size are not effectively treated with mifepristone. Mifepristone is a drug mainly used for abortion and inducing labor, and it has the effect of anti-progestin. Uterine fibroids are estrogen-dependent tumors, and patients taking mifepristone can appropriately reduce the tumor-dependent estrogen, so mifepristone has a certain control effect on uterine fibroids. However, simply taking mifepristone can not make uterine fibroids disappear completely. If the size of uterine fibroids is 5cm and above, it is recommended to go to the hospital for relevant examination to determine whether surgical resection is needed for treatment. Patients should keep a relaxed mood in their daily life, avoid excessive impatience and excitement, and listen to soothing music to relax when they are not in a good mood. Pay more attention to observe the changes in the body, and consult the doctor promptly if there is any abdominal pain, increased menstrual flow, prolonged menstrual period, and so on.