Warts on the belly are caused by human papilloma virus infection of the skin. Warts are a viral skin disease caused by the human papilloma virus infecting the mucous membranes of the skin, thus causing the appearance of benign growths on the skin. The cause of warts is well defined and is a viral infection. Patients with the following predisposing or risk factors are at increased risk of getting warts, including immunocompromise, trauma and especially broken skin. Since there are many types of HPV and the severity of the disease varies with infection, it is important to seek medical attention to confirm the diagnosis of warts on the belly and to follow the doctor’s instructions for treatment. Warts can be treated with topical medications and physical therapy. The most common topical medications include retinoic acid ointment, and physical therapy includes freezing, electrocautery, laser, and photodynamic therapy, as well as interferon, thymosin, and transfer factors to improve the body’s antiviral and immune functions.