Perianal warts can be rubbed with 0.5% tincture of onychomycetin , 5% fluorouracil ointment, 5% imiquimod cream, recombinant human interferon a2b gel and so on. Condyloma acuminatum is a sexually transmitted disease that grows on the vulva, external genital area, and anal area. For treatment, you can use topical drug application and physical therapy. 1.0.5% tincture of onychomycetin, the method is to apply the medicine on the warts, use the medicine twice a day, 3 consecutive days for a course of treatment. If the warts do not fall off, you can use the medicine for three consecutive courses. Adverse reactions are mainly localized pain, redness and swelling, and generally there are no systemic adverse reactions. 2.5% Fluorouracil ointment, topical application 1 to 2 times a day, course of treatment for 2-3 weeks, until the warts fall off, if the surrounding normal skin mucous membrane appears red, swollen, vesicles, it should be suspended. 4.5% imiquimod cream, usually used every day before going to sleep, once every other day, imiquimod does not destroy the skin tissue, but in the external application site can cause erythema, vesicles, edema, exfoliation, scaling and itching, burning sensation, such as mild and moderate irritation. 5. Recombinant human interferon a2b gel, coated with the affected area 4 times a day for 6 weeks. It is recommended that patients with condyloma acuminatum, under the guidance of the doctor to use medication, not to choose drugs without authorization.