After drinking alcohol, panic, shortness of breath and chest tightness, the common clinical causes are angina pectoris, heart failure, drug interactions. 1. angina pectoris: if the sick people themselves have coronary artery stenosis or coronary artery atherosclerosis, their drinking will make the sympathetic nerve excitation, heart rate increases and cause myocardial oxygen consumption increases, thus inducing angina pectoris, the clinical manifestations of the anterior wall of the chest pain, chest tightness, shortness of breath. 2. Heart failure: For people with heart failure, drinking alcohol will increase myocardial oxygen consumption, thereby aggravating heart failure, panic, chest tightness, shortness of breath, dyspnea and other related symptoms become more obvious. 3. Drug interactions: some people have taken cephalosporin antibiotic drugs before drinking, this drug may have a disulfiram-like reaction with alcohol ingested into the body, resulting in chest tightness, shortness of breath, dizziness, nausea, vomiting and other symptoms. If the situation is serious, it is recommended to go to the hospital and receive treatment as soon as possible to avoid delaying the condition.