The precursors of Alzheimer’s disease often manifest as memory impairment, language impairment, dysgraphia, impaired computational skills, personality changes, sleep fragmentation, and temporal and spatial disorientation. Usually, the impairments that appear at this time are not enough to affect the patient’s daily life. However, if left unattended and allowed to develop, it will easily lead to worsening of symptoms and eventually become impossible to take care of oneself, or even complicate other diseases. If the following symptoms occur, the elderly should immediately consult a psychiatrist.1. Impaired memory: Patients can show symptoms such as mildly impaired memory and forgetfulness of recent events, such as not being able to recall what just happened recently or what work was done, and not being able to recall the location of commonly used objects. Patients may ask the same questions over and over again on the same day, so that they are often unable to complete familiar tasks, such as cooking, dressing, etc. However, this phenomenon is often ignored by patients or their families as a result of old-age forgetfulness. 2. Language impairment: Patients may also have symptoms of language impairment, such as forgetting simple words, saying words that cannot be understood, or being unable to name common objects. 3. Some patients may also suffer from dysgraphia, a condition in which they cannot find the right words in their minds, making it impossible to write; 4. Symptoms of indifference include lack of interest in anything, lack of emotion, loss of interest in various activities and hobbies that one used to like, and preferring to stay at home rather than go out; suspicion and paranoia are manifested in distrust of people around, such as suspecting that one’s husband or wife is having an affair, or that the nanny is stealing one’s money, etc.; 6, sleep fragmentation: Patients can show sleep fragmentation, sleeping continuously for 8 hours at night. The patient may sleep for 8 hours continuously at night, but will doze off again during the day. Due to the disruption of physiological rhythms can aggravate the cerebellum to appear amyloid, which is thought to be associated with Alzheimer’s disease. Amyloid fluctuates with the day and night, with levels falling during sleep. If sleep is disturbed or deliberately deprived, or if there is a lack of sufficient deep sleep, the amyloid level inside the brain will rise; 7. Time and space orientation disorder: Some patients may also develop time and space orientation disorder. Time orientation disorder means that the patient cannot distinguish the time he or she is in, and cannot tell if it is morning, noon or night; spatial orientation disorder means that he or she cannot determine where he or she is and can easily get lost. If diagnosed, family members should allow the patient to stay in a familiar environment and continuously support and encourage the patient to maintain previous interests and actively participate in activities to inhibit the progression of the disease.