Patients with defecation difficulties with abdominal pain, may be caused by constipation, intestinal dysfunction, chronic gastroenteritis and other diseases, patients can follow the doctor’s instructions to take lactulose, domperidone, cefixime and other drugs for treatment. 1. Constipation: when the patient suffers from constipation, there may be difficulty in defecation with abdominal pain, the patient can follow the doctor’s instructions to take laxatives, such as lactulose, sorbitol, magnesium sulfate, etc.; pro-dynamic agent, such as mosapride, itopride, etc. for treatment to alleviate the symptoms. 2. Intestinal dysfunction: patients can follow the doctor’s instructions to promote gastrointestinal dynamics of drugs, such as domperidone, mosapride, etc.; digestive drugs, such as multi-enzyme tablets, etc.; antispasmodic and analgesic, such as atropine, etc.; mucosal protection drugs, such as bismuth gel, etc., for treatment. 3. Chronic gastroenteritis: patients can use intestinal probiotics under the guidance of the doctor, such as Bifidobacterium bifidum triple live bacterial bulk, etc.; antibiotics, such as cefixime, erythromycin, etc.; pro-dynamics, such as Itopride, etc., painkillers, such as scopolamine, scopolamine, etc., for patients with Helicobacter pylori infections can be taken to the treatment of omeprazole, pectin bismuth, amoxicillin, metronidazole and so on. It is recommended that patients strictly follow the doctor’s instructions, do not change the dose of drugs or private abuse of drugs, pay attention to the observation of drug reactions in life, if there is any abnormality in a timely manner to seek medical treatment.