Slightly thickened liver spots are usually associated with fatty liver, viral hepatitis and cirrhosis. Oral liver-protecting drugs, antiviral drugs and metabolism-regulating drugs can be chosen according to the cause of the disease. 1. Fatty liver: When the condition of fatty liver worsens and causes diffuse lesions of liver cells, the phenomenon of slightly enlarged liver spots may be detected. Dietary structure can be adjusted, actively participate in exercise, if the diet and weight control is still good, the effect is good. 2. Viral hepatitis: chronic viral hepatitis is relatively more likely, mainly due to liver cell damage. It is recommended to take oral antiviral drugs as soon as possible, such as entecavir, sofosbuvir, etc.; when liver function is impaired, then combined with hepatoprotective and hepatoprotective drugs, such as compound glycyrrhizin. 3. Cirrhosis: when liver tissue hardening occurs, it can also be manifested as thickening of liver spots. The treatment is mainly aimed at the causes of cirrhosis, such as viral hepatitis, fatty liver, alcoholic liver disease and so on. If you need to use the above drugs, you should strictly follow the doctor’s instructions to avoid unauthorized use of drugs.