Inflammation and pus after mole spotting is a manifestation of secondary infection, which can be regulated by general treatment, topical medication, systemic medication and other measures. 1. General treatment: keep the skin clean and hygienic, rinse the wound with saline, local disinfection, clean up the secretion, and at the same time, the diet should be light, and keep the indoor air ventilated and disinfected. 2. Topical medication: After cleaning the secretion, you can use iodophor to routinely disinfect the wound and the surrounding skin, and then apply antibiotic ointment such as mupirocin ointment and fusidic acid cream to treat the wound. 3. Systemic medication: If the area of redness and swelling is large and the infection is serious, you can take oral cefadroxil tablets, amoxicillin capsules and other antibiotic treatment; patients with pain and fever can take ibuprofen, acetaminophen and other drugs for symptomatic treatment. Inflammation and pus after mole spotting, it is recommended to go to the regular hospital in time to check, follow the doctor’s instructions for treatment, do not self-medication.