What about germ cell tumors of the ovaries?

  Patient: When my beloved was 26 weeks pregnant, an ultrasound was performed and a fetal pelvic mass of 2.1*1.4*2.4cm was detected. The baby was born on June 28th as a baby girl, but an ultrasound on the 30th still revealed a pelvic mass of 3.1*2.4*3.4cm, with a liquid dark area and a patchy moderate echogenicity of 2.2*0.9cm at the base of the inner wall, with clear borders. CDFI: no significant blood flow signal was detected.  CDFI: No significant blood flow signal was detected. On July 9, MRI was performed: a 23.8*25.9*22.8mm round abnormal signal was seen above the right iliac fossa bladder, with clear boundaries and uneven signal. There was no abnormal signal within the bladder, and there were no obvious enlarged lymph nodes in the pelvis or ascites. Conclusion: benign occupancy of the right iliac fossa, considering the possibility of teratoid tumor and not excluding complex cysts. There is also a fetoprotein test result: >35350ng/ml. Is surgery necessary? When is the best time to do the surgery? Is there any effect on the baby?  Li Zhanglin, Department of Pediatric Oncology, Tianjin Cancer Hospital: According to your description, it is more likely to be a germ cell tumor from the right ovary. Germ cell tumor is a common congenital tumor in infants and children, which is divided into benign and malignant. Benign includes mature teratoma. Malignant includes immature teratoma, endodermal sinus tumor, embryonal carcinoma, etc. From the information you provided, although normal neonatal AFP can be higher than normal, the AFP in this child is significantly elevated, so the possibility of malignant germ cell tumor is not excluded. The final diagnosis needs to be made by pathology, including the presence or absence of endodermal sinus component, tissue grading, etc. The prognosis of germ cell tumor is very good, with a long-term survival rate of more than 80%. It is recommended that early surgery should be performed to remove the affected ovary together, but laparoscopic debulking of the tumor should be avoided to avoid the possibility of elevated postoperative staging or implantation.  Patient: Does this surgery have any effect on future childbirth? How successful is the surgery? Where hospital did you go for a good surgery?  Li Zhanglin, Department of Pediatric Oncology, Tianjin Cancer Hospital: Removal of unilateral ovary will not affect the endocrine and reproductive functions. The success rate of surgery should be decided by combining the CT examination results to determine the extent of tumor involvement and whether there is spread and metastasis. According to our clinical treatment, the chance of successful surgery is very high. The surgery should be performed in a hospital with experience in pediatric tumor treatment (including surgery and chemotherapy). Again, it is recommended that if laparoscopic surgery is used, tumor removal should be avoided and the affected ovary should be removed together to prevent intraoperative tumor implantation.