Premature ejaculation may be caused by primary premature ejaculation, or chronic prostatitis, chronic seminal vesiculitis, etc. It is necessary to take medication, other treatments for the cause, and surgery if necessary. 1. Primary premature ejaculation: Patients with primary premature ejaculation can use selective 5-hydroxytryptamine reuptake inhibitors such as dapoxetine and paroxetine under the guidance of a doctor. Some patients can also follow the doctor’s instructions with lidocaine gel and other local topical anesthetics coated in the glans area. Men need to enhance self-confidence and reduce anxiety during coitus, and if necessary, they can find a psychiatrist for psychological adjustment. In addition, patients can also take the squeeze method, stop – movement therapy, functional – sex therapy and other behavioral therapy treatment. 2. Chronic prostatitis: For premature ejaculation caused by chronic prostatitis, it is also necessary to use alpha-blockers, such as doxazosin, tamsulosin, etc., as well as doxycycline, levofloxacin and other antibiotics under the guidance of a doctor. For patients with combined benign prostatic hyperplasia, it is also necessary to take prostate electrocision treatment. 3. Chronic seminal vesiculitis: If the patient has premature ejaculation caused by chronic seminal vesiculitis, antibiotics such as cefixime and cefuroxime need to be used under the guidance of the doctor. In addition, some patients can also take the seminal vesicoscopy surgery. It is recommended that patients with premature ejaculation to seek timely medical treatment, the doctor will choose the appropriate measures for the patient’s condition treatment.