The family was very happy when Mr. and Mrs. Xiao Li were happy to have a son, and when they were discharged home from a large hospital in the province, the doctor urged them to return to the hospital 2 days later to review the jaundice, and the family thought that it was nothing important, so they did not go. 5 days later, one night, the little baby appeared not to eat milk, poor response and twitching of the limbs, and was urgently sent to the hospital for examination, and it was found that the child had bilirubin because the jaundice was too heavy and was not treated in time. Encephalopathy, a disease that is about to have serious sequelae, the whole family regrets. So, why does jaundice occur in newborns? Neonatal jaundice refers to unconjugated bilirubin-based jaundice, which is one of the common symptoms in the neonatal period. About 60% of newborns can have varying degrees of jaundice, most of which can subside, while a few children can develop severe hyperbilirubinemia, which can lead to bilirubin encephalopathy in severe cases. Therefore, the diagnostic management of neonatal jaundice is very important. Characteristics of neonatal bilirubin metabolism: 1. Increased bilirubin production: short life span of neonatal erythrocytes, increased sources of bilirubin from paracrine and early markers, and excessive number of erythrocytes. 2.Low bilirubin uptake capacity of hepatocytes. 3. Insufficient ability of hepatocytes to bind bilirubin. 4. Defective bilirubin excretion by hepatocytes. 5, the specificity of hepatic-intestinal circulation: if the excretion of meconium is delayed, it can increase the load of hepatic-intestinal circulation of bilirubin and aggravate the reabsorption of bilirubin. Neonatal jaundice is divided into physiological jaundice and pathological jaundice, and the former can turn to pathological jaundice under certain conditions. As a mother and father, when a new life is born in your family, you must pay attention to observe whether your child has jaundice and, under the guidance of a neonatologist, to identify whether it is pathological jaundice and whether it needs treatment to avoid severe jaundice resulting in bilirubin brain damage.