What are the main drugs that can damage the eyes?

  Although drugs are supposed to treat diseases, if we use improper doses for too long, a variety of side effects of drugs can occur, especially certain drugs can also damage the retina and optic nerve, leading to irreversible vision loss, so we should be reminded that we must pay attention.  So, what are the common drugs that can cause eye damage?  1, hormone: this is a kind of drugs to inhibit the inflammatory response, especially non-infectious inflammation is effective, however, long-term use can cause the following reactions in the eye: ① secondary glaucoma ② concurrent cataract ③ ocular bacterial infection ④ fundus damage is mainly damage to the macula pigment epithelial cells, resulting in central plasma retinal chorioretinopathy, and even limited retinal detachment. In addition, macular edema and optic papilloedema are occasionally seen.  2, chloroquine: is an antiparasitic drug, especially for the treatment of malaria, there are two types of damage in the eye: one is chloroquine deposition in the corneal epithelium or subepithelium, such lesions are reversible and can subside after stopping the drug; the other is damage to the retina, manifested as loss of vision with central dark spot, pigmentation in the macular area of the fundus, and late retinal atrophy. It is an irreversible lesion, and even has a cumulative effect, and the damage is still increasing even after stopping the drug.  3.Quinine: This is a kind of drug for malaria. Large doses of quinine can damage retinal ganglion cells and cause retinal small artery constriction and centripetal narrowing of visual field, which can generally improve after stopping the drug, but if used for a long time, it causes irreversible changes.  4, digitalis: this is a rescue arrhythmia drugs, it can lead to poisoning of retinal photoreceptors, retrobulbar optic neuritis and central inhibition, etc., so as to appear blurred vision, discoloration of visual objects, a significant decrease in vision, a few people can have dark spots or amblyopia.  5, ethambutol: this is a drug for the treatment of tuberculosis, long-term use can occur optic neuritis, mainly damage the macular bundle of the optic papilla, and therefore produce vision loss, central dark spot and color vision impairment, this damage is reversible, when the lesion improves vision can be restored, and again with the drug vision is not reduced.  6, chloramphenicol: generally 1-2 grams per day for adults, for a month can cause toxic optic neuritis, after discontinuation of some patients can be improved, but some patients develop optic nerve atrophy, and even blindness, especially children are more likely to occur.  7, streptomycin: a commonly used antibiotic, anti-tuberculosis drugs, which in addition to the impact on the auditory nerve, can also damage the optic nerve, causing sudden retrobulbar optic neuritis or progressive optic nerve atrophy.  In addition, isoniazid, aspirin, anti-inflammatory pain, POTUS powder and chlorpromazine and other drugs can produce a certain degree of damage to the retina and optic nerve.