In recent years, the incidence of allergic diseases has been increasing year by year due to the influence of multiple factors such as climate and environment (e.g., bronchial asthma in children, cough variant asthma, allergic rhinitis, eczema, acute and chronic urticaria, allergic enteritis, contact dermatitis, drug or food allergy, etc.). The key to satisfactory treatment of allergic diseases lies in the accurate identification of the causative allergens (allergens) and their avoidance or targeted immunotherapy. However, unfortunately, the medical market for allergen testing is relatively chaotic, with a variety of inaccurate, non-standard, non-scientific and even pseudo-scientific testing methods flooding the land, making it difficult for patients to distinguish the true from the false. The reason for the proliferation of these unscientific methods is, first, the profit-driven medical side; second, the patient’s naive desire to use the shortest time, the simplest way to solve the psychological pain; third, people’s (including some doctors) ignorance of allergen detection technology. It is reported that some medical units in the society (including individual tertiary hospitals) use unreasonable and unscientific allergen detection methods to deceive the majority of patients, including bioresonance, microchips, traditional Chinese medicine, etc. for allergen diagnosis and treatment. Bioresonance is a kind of imported medical equipment originated in Germany and for various reasons obtained legal status in China a few years ago, misleading patients with non-invasive, painless, no side effects, short treatment time and high cure rate, claiming that only patients need to hold two probe-like things in both hands for more than 10 minutes to lock allergens in hundreds of suspicious substances, and for the detected allergens can also use almost the same approach to desensitization treatment in a short period of time. As a result, many patients who are tired of formal allergen diagnosis and treatment and need multiple blood draws and long-term injections began to favor this instead. However, many well-known experts in the field of allergic reactions (commonly known as allergies) in China do not agree with this, and Professor Zhang Hongyu, chairman of the Chinese Medical Association’s Allergic Reaction Society, who is quite indignant about this, clearly told everyone that this treatment lacks evidence-based medical evidence and is pseudoscientific. Professor Yin Jia, secretary-general of the Chinese Medical Association’s Society of Allergic Reactions, said. However, when they continue to seek medical advice and buy useful drugs, they often have no money in their pockets and do not get the treatment they really need, delaying the best time for treatment. In addition, there are also some unscientific and irregular desensitization therapies circulating in the society, which waste patients’ time and money and fail to achieve therapeutic effects. The formal allergen-specific diagnostic tests are in vitro and in vivo tests (intradermal, prick, patch, excitation test, etc.); Uni CAP (Immuno CAP 100 and Immuno CAP250, etc.) is a fully automated in vitro allergen testing system manufactured by the Swedish company Farmacia, an advanced laboratory system consisting of highly automated instruments, in vitro testing reagents and related software. The Uni CAP is the first fully quantitative test approved by the FDA and is recognized by the international allergist community as the gold standard for in vitro allergen testing due to its high sensitivity, specificity and stability, and is also recognized as a scientific method in international journals. It is also recognized as a scientific method in international professional journals. It is easy, safe and fast to get accurate test results by simply taking a blood sample. It can detect inhalant allergens screening (containing 95% of common major inhalant allergens in the air, such as plant pollen, household dust mites, dust mites and other mites, mixed animal dander, etc.), food allergens screening (e.g. soy, peanut, egg, milk, wheat and fish), total IgE and specific IgE of about 600 allergens. By taking a detailed medical history of the patient with allergic diseases and performing relevant specific tests to clarify the allergens, and after the diagnosis is established, the clear allergens should first be avoided and removed as much as possible. However, inhalant allergens such as airborne dust mites are common and unavoidable, so desensitization is particularly important and should be performed as early as possible. Desensitization is academically known as immunotherapy and is the only treatment recommended by the World Health Organization (WHO) that has the potential to alter the natural course of allergic diseases through immunomodulatory mechanisms (also known as the root cause). The allergen is made into different concentrations of preparations, from low to high concentrations of injections to patients regularly, through repeated injections to make the patient tolerant to the allergen, so that when they are exposed to the allergen again, the symptoms of attacks are significantly reduced or do not develop, with the dual significance of treatment and prevention, and the efficacy is long-lasting. Clinical indications: insect venom desensitization, nasal mucosa and asthma such as: hay fever, mite origin, animal hair and dander, mycosis and other allergic diseases that require longer-term regular maintenance treatment. In summary, patients with allergic reactive diseases should be promptly examined and treated at a regular hospital. Patients should ask whether the in vitro allergen testing is the Uni CAP fully automated in vitro allergen testing system recognized by the international academic community of allergists, and whether the treatment is performed by professionally trained medical personnel. Formal in vivo allergen testing methods are intradermal, prick, patch, and provocation tests, and standardized allergen reagents must be used. Specific immunotherapy, at present, is mainly injection therapy and sublingual immunotherapy. We hope that you will seek early diagnosis and get rid of allergic diseases.