Although the incidence of bacterial cold is low, once it occurs, the patient’s systemic inflammatory response will be heavier compared with viral cold, while most patients are accompanied by symptoms of fever. Antibiotics, antipyretics and analgesics, anti-allergic drugs, Chinese medicines, etc. can be used according to the specific situation.1. Antibiotics: If it is caused by common bacterial infection, antibiotic treatment of cephalosporins, amoxicillin and azithromycin can be preferred. antibiotics of quinolones, such as levofloxacin, can be preferred for people over 18 years old. It should be emphasized that the application of antibiotic treatment usually requires at least 3 days of administration. Among them, azithromycin has a long drug half-life, and the drug efficacy can be maintained for 5-7 days after 3 days of oral administration. The rest of the antibiotics can be discontinued after 3 days if the symptoms are relieved, and can be continued for 5-7 days if necessary; 2. Antipyretic and analgesic drugs: If the body temperature exceeds 38.5°C, you can consider taking oral non-steroidal antipyretic and analgesic drugs, such as ibuprofen, acetaminophen tablets, etc. If necessary, you can choose anti-inflammatory pain suppositories Anal plug treatment, but do not use it continuously to avoid adverse reactions such as excessive sweating and deficiency. A few patients may also experience adverse reactions such as rash, leukopenia, and drug fever. During taking antipyretic drugs must be supplemented with more soup to reduce complications caused by water and electrolyte loss; 3, anti-allergy drugs: for cold patients with khat symptoms, such as nasal congestion, runny nose, sneezing, etc., you can choose anti-allergy drugs, such as loratadine, cetirizine and other drugs as appropriate to relieve discomfort; 4, proprietary Chinese medicine: clear heat and detoxification of proprietary Chinese medicine, such as Banlangen granules to relieve systemic discomfort Symptoms also have a certain effect.