Panic and lack of strength legs are very heavy according to the specific reasons to decide how to treat, the main common causes of panic weakness and lower limb heaviness can be divided into non-pathological reasons and pathological reasons. 1. Non-pathological reasons: when overwork, mental stress, drinking strong tea may cause temporary panic and weakness, feel heavy feeling in the lower limbs, at this time there is no need for special medication, through rest, relaxation can be restored. 2. Pathological causes: when hypoglycemia, anemia, cardiac arrhythmia, coronary heart disease and hypothyroidism will have panic, weakness and other symptoms, according to the cause of treatment. (1) Hypoglycemia can be relieved by timely supplementation of sugar, such as drinking an appropriate amount of sugar water. (2) Iron deficiency anemia can be relieved by taking iron supplements such as ferrous succinate. (3) Antiarrhythmic drugs such as amiodarone and metoprolol can be used when there is arrhythmia. (4) Coronary artery disease patients according to the situation of choice of interventional therapy, and long-term oral antiplatelet such as clopidogrel, aspirin, etc., lipid regulating and stabilizing drugs such as pitavastatin, atorvastatin, etc.. (5) Hypothyroidism requires oral levothyroxine sodium tablets to supplement thyroxine. When patients repeatedly panic, fatigue and other symptoms, it is recommended to consult a doctor in a timely manner, under the guidance of a professional physician to improve the relevant examination to clarify the cause of the standardized treatment, do not take medication without authorization, resulting in adverse consequences.