Metronidazole and cephalosporin are both commonly used antibiotics, but belong to different categories, taken together can produce a coordinated effect to play the anti-infective effect, patients should pay attention to the correct take under the guidance of doctors. The main role: 1, metronidazole: metronidazole belongs to the nitroimidazole class of antibiotics, suitable for the treatment of trichomonas, amoebic protozoa and a variety of anaerobic bacteria caused by tract diseases, including intestinal and extra-intestinal amoebiasis, vaginal trichomoniasis, etc.; 2, cephalosporin: cephalosporin antibiotics, belonging to the broad-spectrum antibiotics, can be used to kill most Gram-positive and negative bacteria, mainly for the treatment of various sensitive bacteria caused by Infectious diseases, such as upper respiratory tract infections, abdominal cavity diseases, skin diseases and urinary tract infectious diseases, etc. Precautions: 1. When metronidazole and cephalosporin are used at the same time, it is recommended to take them half an hour after meals, because these two types of drugs have a certain stimulating effect on the gastric mucosa and intestines, which can easily cause gastrointestinal reactions, such as nausea, vomiting, loss of appetite, etc., and may cause abdominal cramps in severe cases; 2. Toxic reactions can occur, leading to poisoning of patients, and even life-threatening in serious cases.