Patient: last menstrual period June 2, 2009, ovulation June 21, July 2 there was a little vaginal bleeding (brown discharge), self-test urine HCG weak positive, July 3 blood HCG 8.4, progesterone 12.81, the doctor recommended rest at home, oral folic acid, vitamin E, no vaginal bleeding from July 6, July 9 vaginal bleeding again, dark red, less than the menstrual flow, no There was no blood clot. HCG 25.78, progesterone 5.15, vaginal ultrasound, no gestational sac in the uterus, no abnormality in the adnexa. The doctor said it was a biochemical pregnancy. If it is a biochemical pregnancy, has the fertilized egg been deposited in the uterus? What is the difference between ectopic miscarriage and biochemical pregnancy? How long does it take to get pregnant after a biochemical pregnancy? Lina Guo, Department of Reproductive Medicine, The Fourth Hospital of Hebei Medical University: Hello! 1, biochemical pregnancy, the fertilized egg must have already deposited and contacted with the mother, otherwise HCG can not be measured in the blood of the mother, but exactly where it deposited, whether it is the endometrium or ectopic can not be clarified, it may be in both parts of the body. 2, ectopic pregnancy is already a clinical pregnancy (i.e., a relatively clear site of pregnancy), biochemical pregnancy is not yet considered a clinical pregnancy. There are some early menopause HCG elevation (especially after IVF embryo transfer HCG elevation) B ultrasound intrauterine and extrauterine did not see the gestational sac, biochemical pregnancy and ectopic pregnancy is still not good to distinguish. Generally, the HCG value of biochemical pregnancy is low, there is a transient increase, and then return to normal, ectopic pregnancy HCG value is generally higher, but the growth rate is slow, and will not fall down soon. 3, biochemical pregnancy does not affect the next pregnancy, do not have to wait a period of time to try to get pregnant again.