Tightness of chest, shortness of breath, panic and thirst can be improved by drinking water and resting if the symptoms are physiological, but if they are caused by pathologic conditions, such as massive blood loss and hypertonic dehydration, they need to go to the hospital for further treatment. Normal people can also have symptoms of chest tightness and shortness of breath, panic and thirst, for example, after a long period of strenuous exercise, if you give supplemental saline water and rest, the symptoms can be slowly relieved, and no special treatment is needed. These symptoms can also be seen in pathologic conditions such as hyperthyroidism, massive blood loss, and hypertonic dehydration. To determine the cause, it is necessary to take into account the medical history and symptoms. For hyperthyroidism, anti-thyroid medication such as propylthiouracil can be applied; for massive blood loss, it is necessary to take into account the condition of the patient and the laboratory tests, and if it is serious, blood transfusion should be given to correct the anemia; for hypertonic dehydration, it is necessary to give rehydration fluids, and to pay attention to maintaining the balance of sodium and potassium. It is difficult to identify the cause of the symptoms alone. If the symptoms continue to be unrelieved, it is best to go to the hospital to find out the cause of the disease and choose the appropriate treatment.