Dry eyes, dry nose, dry throat, dry mouth without thirst are considered to be related to physiologic factors and dry syndrome. It is recommended to detach from the environment, pay attention to water supplementation, and give appropriate medication under the guidance of a doctor. 1. Physiological factors: usually do not pay attention to water supplementation, often in a dry and windy, hot and cold environment leading to a large amount of water loss, can cause symptoms of injury. It is recommended to get out of the environment, pay attention to water supplementation, eat more fresh fruits and vegetables, and wear masks and glasses when you go out, which can help alleviate the symptoms. 2. Dry syndrome: the cause and pathogenesis of dry syndrome are not yet completely clear, patients may have dry mouth, tongue dry and cracked, dry conjunctivitis, nasal dryness, dry throat, vulvar and vaginal dryness, itching, pain and other symptoms. Methotrexate, prednisone, celecoxib, sodium vitrate eye drops, bromoacetyl tablets and other medications can be given under medical supervision. Patients are advised to pay attention to life and dietary care, if necessary, go to the ENT department of the hospital for examination, if it is caused by pathological factors, it is recommended to follow the doctor’s instructions to give medication for the cause of the disease.