Foot blisters are not caused by bacterial infections, but rather by fungal infections of the skin caused by the fungus ringworm, which invades the cuticle. In addition to tinea pedis, ringworm and ringworm of the head are caused by dermatophyte infections. There is a difference between fungi and bacteria. Fungi are eukaryotic microorganisms that have their own nucleus, while bacteria do not have their own nucleus. Fungal infections are mainly treated with oral or topical antifungal medications. Commonly used oral medications include itraconazole, terbinafine hydrochloride tablets, and topical medications include terbinafine hydrochloride cream, naftifine ketoconazole cream, luliconazole cream, etc. Some patients with foot fungus can also be infected with bacteria because of the formation of vesicles after the blisters have broken down.