Coronary heart disease can be improved by taking nitrate drugs, beta-blockers, calcium antagonists and antiplatelet drugs to improve chest tightness and shortness of breath. Nitrate drugs such as nitroglycerin and isosorbide mononitrate; these drugs can dilate the coronary arteries, reduce pressure, dilate the veins, reduce the amount of return blood, reduce the symptoms of myocardial ischemia, thus improving chest tightness and shortness of breath. Beta-blockers such as propranolol and metoprolol, and calcium antagonists such as verapamil and diltiazem can improve chest tightness and shortness of breath by lowering heart rate and reducing myocardial oxygen consumption. Antiplatelet drugs such as aspirin and clopidogrel, which prevent platelet aggregation, plaque formation, and increase blood supply to the distal myocardium, may also improve chest tightness and shortness of breath. All of the above drugs have adverse effects, and it is recommended that they be used in a standardized manner under the guidance of a physician to avoid adverse effects.