Acute upper respiratory tract infections are mainly caused by viral or bacterial infections. Their medication should be selected on an individual basis. Bacterial infections can be treated symptomatically with antibiotics. For viral infections, there are no specific antiviral drugs, and the main treatment is symptomatic, as follows: 1. Decongestants: mainly compound pseudoephedrine; 2. Antihistamines: mainly chlorpheniramine; 3. Cough and phlegm medicines: phlegm medicines are commonly used, such as aminoglutethimide, and Chinese medicines are lozenges and pharyngitis tablets. In case of severe cough, central cough suppressants can be used, mainly dextromethorphan. For specific medication, please combine with clinical practice and be guided by a doctor’s interview.