Almost every cardiologist will encounter such difficult patients, they often come to the hospital because of heart symptoms such as panic, chest tightness, shortness of breath, chest pain, but long-term outpatient clinics in major hospitals through all levels of doctors, and even expert outpatient diagnosis and treatment are not relieved, the more the problem is seen, the more drugs eat more and more, the body is getting worse, patients and families think they have some kind of difficult disease, more and more The more patients and their families think that they have some kind of difficult disease, the more worried and worried they are, the more efforts they make, the more they ask for good doctors and medicines and spend a lot of time and energy. For example, the patient feels panic and palpitations all day long, but the 24-hour electrocardiogram test has no obvious arrhythmia, and the patient feels shortness of breath with slight activity, but the cardiac ultrasound shows good systolic and diastolic function. 2. There are many symptoms with cross-system characteristics, such as cardiovascular symptoms such as chest tightness, shortness of breath, and male pain, but also a large number of neurological, digestive, urinary, etc., such as dizziness, headache, insomnia, bloating, indigestion, constipation, diarrhea, urinary urgency, polyuria, sweating, numbness of hands and feet, etc. Therefore, it is difficult to be explained by simple heart disease, and doctors often have to ask patients to go to the relevant departments for their own consultation The problem can be solved. Patients often have a lot of worries, that is, they are worried about not being able to find out the disease and the danger of having heart disease sooner or later, and they are worried that it is unsafe to go for related examinations and bring pain, and most of all, they are worried about the adverse drug reactions, and the more they study the instructions of various drugs, the more they are afraid to take them or change them frequently. These patients are actually not a minority, and if analyzed only from a cardiovascular perspective, it is indeed difficult to explain so much discomfort. But from an overall perspective and from a psychological point of view, these patients all have different degrees of anxiety and depression or symptoms, such as excessive worry, nervousness, easy fright, fatigue, depressed mood, upset, insomnia, diminished interest, and unhappiness, only that these bad emotions are treated by everyone as psychological reactions to long-standing heart disease, without any direct connection with heart disease symptoms. So what are the causes of these symptoms? Medical psychology research has found that psychological factors can lead to some somatic symptoms through a series of psychophysiological reactions, which we call somatization symptoms, in which the intermediary link is sympathetic-parasympathetic system (formerly called vegetative nervous system), endocrine-nervous system, because the vegetative nervous system is widely distributed throughout the body, its dysfunction will of course produce dysfunction of all systems in the body, which is the reason why anxiety and depression patients’ symptoms This is the reason why the symptoms of anxiety and depression patients are more frequent and cross-systemic. Since somatization symptoms such as panic and chest tightness are more prominent, many anxious and depressed patients come to the cardiology department with symptoms similar to those of heart disease.