The parapharyngeal space, also known as the maxillary pharyngeal space, is the interconnecting hub between the major fascial spaces. Various infections from the parotid, occlusal, peri-tonsillar and submandibular spaces can spread to the parapharyngeal space and from there to the retropharyngeal space and even to the chest. The clinical manifestations of parapharyngeal space infections are mainly pain in the pharynx and neck, aggravated by swallowing movements, mouth opening, and neck movement. The infection of the anterior stem space involves the internal pterygoid muscle with difficulty opening the mouth, or even inability to open the mouth, resulting in dental closure. Systemic symptoms usually include high fever, chills, loss of appetite, headache, and fatigue. In severe cases, the patient may be in a state of severe failure.