Drug balloon treatment requires lifelong medication. Drug balloon is mainly used for the treatment of coronary heart disease, some patients with thin blood vessels, implantation of stents may be higher risk of restenosis, can be treated by drug capsule, in the improvement of blood supply of blood vessels at the same time, can be released locally drugs, long-term role, and at the same time need to long-term oral acepromazine, atorvastatin and other drugs. Coronary heart disease secondary to coronary atherosclerosis, once coronary heart disease can not be completely cured, regardless of whether the patient is treated with drug balloon therapy, patients need to take medication for life, to avoid the progression of the disease, to alleviate the symptoms of angina pectoris, reduce the incidence of myocardial infarction. Aspirin is a drug that belongs to the inhibition of platelet aggregation, the adverse reactions of the drug are stomach pain and bloating, gastrointestinal bleeding, bleeding of the skin mucous membranes, etc. It is forbidden to use it for patients who are allergic to the components of the drug, aspirin-related asthma, active bleeding, active ulcers, hemophilia and so on. The main role of atorvastatin is to stabilize plaque and reduce blood lipids, the adverse effects of the drug include nausea, vomiting, myalgia, arthralgia, etc. It is contraindicated in patients with allergy to drug components, unexplained elevated liver enzymes, and severe hepatic function impairment. Specific follow-up treatment is recommended to consult the attending physician’s opinion, under the guidance of the physician to receive further treatment.