The non-stop hiccups are mainly related to the following factors: 1. special food eaten, such as too cold sorbet, ice cream, too hot spicy hot, drinking too many carbonated drinks, overeating, long time dieting without eating, drinking alcohol, eating too fast, etc. 2. diseases seen in the central nervous system, such as meningitis, brain hemorrhage, brain tumor, brain infarction, etc. 3. diseases that can be seen outside the central system, such as esophageal cancer, thoracic aortic aneurysm, etc. At the same time, we should pay attention to the improvement of relevant examinations to exclude lesions in the brain and esophagus, and actively perform treatments such as promoting gastrointestinal tract dynamics.