There are many causes of diarrhea with blood, usually associated with bacterial dysentery, intestinal polyps, ulcerative colitis, Crohn’s disease, and colorectal cancer. Targeted treatment is needed to alleviate symptoms after identifying the cause. Common causes and treatment 1, bacterial dysentery: the disease is often caused by unclean diet, mainly manifested as fever, abdominal pain, diarrhea, shortness of breath, mucopurulent stools and other symptoms. Diet should be mainly liquid food, avoid eating cold, greasy things, such as ice cream, fried chicken, etc.. Drug treatment is based on oral antibiotics, such as ciprofloxacin, but infants, children and lactating women should be used with caution; 2, intestinal polyps: stool stimulation of polyps growing on the surface of the intestinal mucosa, resulting in blood in the stool, the blood is bright red. Generally take endoscopic polypectomy for treatment, in addition, the daily diet should increase the intake of dietary fiber, more cereals, fruits and vegetables, such as millet, cabbage, oranges, etc.; 3, ulcerative colitis: due to intestinal mucosa erosion, congestion, which in turn leads to symptoms such as mucus pus and blood stool, in addition to this, can also be accompanied by abdominal pain, diarrhea and other symptoms. It is usually treated with aminosalicylic acid preparations, such as salazosulfapyridine, olsalazine, mesalazine, etc., under the guidance of a professional physician. If symptoms such as hemorrhage and intestinal perforation occur, immediate surgical treatment is required; 4. Crohn’s disease: the cause is still unclear, often showing symptoms such as abdominal pain, diarrhea, mucopurulent stools. In life, patients should pay attention to rest, eat more high-protein, low residue food, common therapeutic drugs include aminosalicylates, hydrocortisone, levofloxacin, immunosuppressants, biological agents, etc.; 5, colorectal cancer: due to the fecal mass rubbing the tumor or ulcer surface, so that it breaks, at which time the fecal mass is stained with fresh blood, mucus, or even pus. Surgical resection is the main treatment means, in addition, it can be combined with chemotherapy and other means for adjuvant treatment.