Clinically common skin cysts include sebaceous cysts, epidermoid cysts, popliteal cysts, etc., which are basically benign lesions. Most skin cysts are not serious, but in the following cases, skin cysts need to be treated surgically as soon as possible to avoid serious complications: a. Larger popliteal cysts, once the compression of the popliteal artery and nerve, patients can appear lowered skin temperature of the lower limbs, abnormal sensation. At this time, if surgery is not performed as soon as possible, the symptoms of swelling and pain in the lower limbs will gradually worsen and cause more serious complications. Therefore, patients need to undergo surgery to remove popliteal cysts as soon as possible and avoid residual cyst walls during surgery to avoid recurrent attacks of cysts. Second, for facial sebaceous cysts, once combined with infection, if repeatedly squeezed may cause local bacterial invasion of the skull, causing intracranial infection. Patients can control the local infection through external rubbing of Bactrim ointment and then perform surgical excision as soon as possible to achieve a better treatment effect.