What is the real cause of death from smog? Smoker’s disease is a cerebrovascular disease of unknown etiology characterized by chronic progressive stenosis or occlusion of the terminal internal carotid arteries and the anterior and middle cerebral arteries bilaterally, and secondary to the formation of an abnormal vascular network at the base of the skull. The symptoms of smoker’s disease are mainly divided into cerebral ischemia and cerebral hemorrhage, etc. Among them, cerebral ischemia caused by vascular stenosis can cause headache, dizziness, and lack of concentration. A more severe case may cause numbness of the limbs and weakness of the limbs. If it is more severe, it may cause hemiplegia and aphasia. Smog can also lead to cerebral infarction if it is a large cerebral infarction it can lead to stroke and this can lead to death. Also cerebral infarction may lead to visual field defects, aphasia, etc. And cerebral hemorrhage caused by overdistension of the compensating blood vessels may cause sudden severe headache with nausea and vomiting, etc. The main cause of death from smog is also due to cerebral hemorrhage. Patients should be treated as soon as possible after the diagnosis of smog to prevent brain hemorrhage. The clinical treatment of smog is based on direct bypass surgery, indirect bypass surgery, and combined vascular bypass surgery. Direct bypass surgery refers to the re-establishment of new blood channels to ensure adequate cerebral blood flow, and to rapidly improve cerebral blood supply by directly bypassing the intracranial and extracranial vessels to anastomose. Indirect bypass surgery, or patching surgery, is the application of muscle and meningeal tissue rich in extracranial blood supply to the surface of the brain inside the skull. To relieve the inadequate blood supply to the intracerebral arteries, the blood flow in the brain is improved by establishing a channel for the normal blood vessels outside the brain to supply blood to the brain. After the blood supply is improved, the demand for smoke-like vessels will be reduced, thus reducing the risk of re-occurrence of cerebral ischemia and cerebral hemorrhage in patients. Combined vascular bypass surgery is a combination of direct bypass surgery and indirect bypass surgery, i.e., two surgeries performed in the same operation, and is the most commonly used surgical treatment in clinical practice. It has the advantage of solving the problem of cerebral ischemia at once. The operation is more operable and safe, and the surgical effect is maximized with immediate results. Can smoker’s disease be cured? Smoker’s disease is a chronic progressive disease and there is no curative drug or surgical treatment available at this time. Because combined vascular bypass surgery cannot open the occluded blood vessels, it can only improve them, so technically speaking, there is no cure for smog. However, combined vascular bypass surgery is to re-establish new blood flow channels and to induce the formation of neovascularization to improve the lack of blood supply to the brain, and with neovascularization, the compensating vessels will not be overly dilated and cause brain hemorrhage, which can lead to death. Therefore, even if the occluded cerebral blood vessels cannot be opened, combined vascular bypass surgery is still possible to treat smog disease. According to a large number of clinical evidence, patients’ symptoms will be improved after the combined bypass surgery. It does not affect the patient’s normal life. Combined vascular bypass surgery is still the only effective treatment for smog. Patients should seek medical advice and arrange for appropriate surgical treatment if they have such a need.