Generally, induction of labor at 16 weeks of pregnancy takes about 24 to 48 hours to expel the fetus, but there may be individual differences. When inducing labor at 16 weeks of pregnancy, you need to follow the doctor’s instructions to do intra-amniotic injection of drugs (esacridine, etc.) to terminate the pregnancy, which should be operated by a professional doctor, and exclude contraindications such as hepatic and renal insufficiency before the use of the drug, as well as improve the gynecological examination, blood and urine routine, blood coagulation function and other related examinations. Generally, the fetus can be discharged about 24~48 hours after the medication is administered, but there will be individual differences. After induced abortion, we should pay attention to appropriate rest, avoid premature physical labor and strenuous exercise, keep the vulva clean and dry, change and wash underwear, prohibit tub baths and sexual intercourse for one month, increase diet and nutrition to promote physical recovery, follow the doctor’s instructions to give cefixime and other drugs to prevent infection treatment, observe the vaginal bleeding, and be on time for review.