It is the responsibility of the human immune system to maintain a certain level of sensitivity to a variety of substances inside and outside the body. Our organism is challenged daily by foreign factors such as microorganisms, foreign substances (food/drugs/dust/dust mites), and tumor cells, but they are usually quietly eliminated by the body’s immune system, so that a well-functioning immune system keeps our organism free from infectious diseases and tumors. Hypersensitivity, also known as hyper-) sensitivity, is very common in the population. Due to the diversity of substances inside and outside the body, our immune system cannot adequately distinguish what is harmful and beneficial to the organism, and occasionally a strong immune response occurs to some foreign substances or mutations, resulting in clinical discomfort such as rashes, itching, sneezing, diarrhea, asthma, and many others. Therefore, allergies occur to a greater or lesser extent in everyone’s life. The good thing is that for the majority of people, these abnormal allergic reactions are not too long-lasting and cause minimal damage to the body due to our own strong immune recognition and immune regulation mechanisms. Atopic dermatitis, also known as “atopic dermatitis, genetic atopic dermatitis”, is a chronic inflammatory skin disease associated with genetic allergic qualities. The name atopic originates from modern Western medicine, where atopic means that the patient has a genetic susceptibility to the disease, i.e., the patient’s immune system has some defect at the genetic level, which makes the body’s immune system susceptible to an abnormal immune response to a variety of factors, both internal and external (that should be tolerated), compared to a normal person, and produces high levels of atopic dermatitis in response to exposure, ingestion, inhalation, or multiple substances in the body. The high level of immune response to a variety of substances in the body or in contact with them is manifested clinically as itching, erythema, papules, blisters, vesicles and other skin damage, often accompanied by allergic rhinitis, asthma, etc. In more general terms, the immune system of atopic dermatitis patients is in a state of irritability. Multiple members of the same family live, eat, and are exposed to roughly similar substances, and only patients with atopic dermatitis have the disease due to their own immune deficiency. With the change in climate and environment and the acceleration of urbanization, the incidence of atopic dermatitis seems to be higher in the higher socioeconomic classes. As early as 30 years ago, some foreign scholars proposed the hygiene hypothesis of the disease: too much attention to hygiene in early childhood seems to have an inducing effect on the development of atopic dermatitis. The most prominent clinical manifestation in patients with atopic dermatitis is itchy skin, often aggravated by heat or washing at night. The skin is drier than normal, especially in the cold season, and the extremities first appear scaly. Repeated conscious or unconscious scratching causes the skin to thicken and take on a leathery appearance, aggravating the pruritus and thus creating a vicious cycle. Laboratory tests often reveal elevated blood IgE levels, elevated eosinophils, and positivity to several allergens. The condition can last for years and decades, and in severe cases, erythematous flaking around the body, also known as erythroderma, can develop, requiring hospitalization to relieve the condition. Because the development of atopic dermatitis is related to the patient’s allergic qualities (constitution), an ideal treatment is lacking. For most patients, long-term, all-round comprehensive prevention and treatment is required. Since these patients generally have dry and dehydrated skin and impaired skin barrier function, and thus are highly susceptible to various irritants and microorganisms in the environment, frequent and regular use of emollient moisturizers has become the first recommended treatment method at home and abroad; for limited erythematous and papular lesions depending on the lesion area, moderate and weak corticosteroid creams can be used for external application, and for stubborn leather-like lesions, strong For the stubborn leathery lesions, the super-strong hormones need to be applied inside and outside for a short period of time; non-hormonal anti-inflammatory drugs such as tacrolimus can be used topically if the economic conditions are better; for patients with more extensive lesions, UVB and other phototherapy can be used; of course, for severe erythrodermic type patients, they need to be treated with immune agents such as methotrexate and cyclosporine in the hospital system. For the daily care of patients, we need to pay attention to less flowers and pets at home, keep indoor ventilation and light to eliminate room mites; wear cotton underwear; try not to use detergents when bathing; avoid wine, seafood, beef and mutton, bamboo shoots, pickled products, onions and other stimulating diets; drink yogurt appropriately to adjust the intestinal flora.