Yellow tumors, referred to as xanthomas, are benign tumors. Yellow tumors can be divided into two categories: yellow tumors without hyperlipidemia and yellow tumors with hyperlipidemia. The former is most common in xanthomas of the eyelid, while the latter is most common in diabetic xanthomas and multiple nodular xanthomas. The former is the most common type of xanthoma of the eyelid, and the latter is the most common type of diabetic xanthoma and nodular xanthoma. There are no symptoms other than cosmetic effects. Most patients do not have significant peripheral metabolic disorders, but some patients may have hyperlipoproteinemia, which should be examined for early atherosclerosis. Extensive yellow tumors are seen in patients with biliary cirrhosis and histiocytosis such as cutaneous reticulohistiocytoma. Diabetic yellow tumors are seen in patients with diabetes mellitus, mostly in clusters in the skin areas of the palms and plantar areas of the feet. Because yellow tumors may involve disorders of lipid metabolism, systematic examination should be performed to prevent and treat systemic diseases. Treatment of yellow tumors: excisional suture treatment is feasible for small areas; if the area is large, the trauma should be repaired with full-thickness or medium-thickness skin implants. In the eye, eyelid ectropion should be prevented from occurring, and yellow tumors of the eyelid are prone to recurrence after surgery. In addition to surgical treatment, laser, high-frequency electrical or chemical cautery treatment is also available. In cases of xanthomas due to systemic disease, the xanthomas generally do not subside during the course of drug treatment of the primary disease. Because yellow tumors of the eyelid are not self-healing and grow progressively, affecting the patient’s appearance, the doctor reminds patients to seek early treatment.