For women who are about to become mothers, there is a lot of concern about folic acid supplementation. Although folic acid is widely present in almost all foods, most of the folic acid in food has actually been destroyed due to our traditional high-temperature frying and boiling cooking methods. Moreover, the absorption rate of folic acid in human intestine is only 25%-50%, and the maternal need for folic acid increases during pregnancy, blood dilution and plasma clearance increases instead, so it is easy to make the production, transformation and metabolism of folic acid abnormal, resulting in a serious deficiency of folic acid in our women of childbearing age. Especially for patients with gastrointestinal problems, such as chronic gastritis and atrophic gastritis, the absorption of folic acid is even worse. Generally speaking, if a woman is preparing for pregnancy or is already pregnant, it is better to take 400 micrograms of folic acid tablets (equivalent to 0.4 mg) rather than 5 mg of folic acid tablets prescribed by the hospital, because too high a concentration of folic acid is sometimes not very good for the fetus. Some time ago there was an article about the dangers of folic acid overdose. This is why I always ask expectant mothers to buy folic acid tablets for pregnant women outside of the clinic. It is not that I am not willing to prescribe you medication that can be used at public expense, but because this dosage form is mainly used for anemia treatment and is a bit more concentrated for pregnant women. If some women are already using highly concentrated folic acid tablets, there is no big problem with short-term use, drink more water, folic acid is still excreted quickly, just correct the dose as soon as possible.