Sexual disorder premature ejaculation available drugs are many, patients can be treated by 5-hydroxytryptamine reuptake inhibitors, tricyclic antidepressants, topical delay and other drugs. 1. 5-hydroxytryptamine reuptake inhibitors: representative drugs such as dapoxetine are suitable for the treatment of male premature ejaculation patients aged 18-64 years. When using Dapoxetine, patients need to pay attention to the fact that it is forbidden to use it in people who are known to be allergic to the product, forbidden to use it in patients with obvious pathological conditions of the heart, and forbidden to use it in patients with moderate and severe liver injury. 2. Tricyclic antidepressants: such as chlorpromazine, etc., the main effect is to block the central nervous system norepinephrine and 5-hydroxytryptamine reuptake, can play the role of antidepressant and anxiolytic, sedative and anticholinergic effect. Clinical athletes should be cautious, allergic to the components of the drug is prohibited. 3. Topical prolongation drugs: such as lidocaine jelly, is a kind of amide drug. Lidocaine through the inhibition of the sodium channel of the nerve cell membrane to stabilize the nerve cell membrane, blocking the role of nerve excitation and conduction. Clinical allergy to the components of the drug is prohibited. The above drugs in the treatment of sexual disorders premature ejaculation have a certain effect, the patient should be under the guidance of the doctor to choose the medication, do not use the drug privately, if there is any discomfort in a timely manner to consult and treatment.