Diabetic peripheral neuropathy can be treated with medications as prescribed by the doctor, including hypoglycemic drugs and nutritive nerve medications. Patients with diabetic peripheral neuropathy can use hypoglycemic drugs or insulin as prescribed by the doctor to control blood glucose in a reasonable range, so as to reduce the irritation and damage to the peripheral nerves. Some patients can use vitamin B12 and other B vitamins to improve the metabolic disorders of nerve tissues, and also can use gangliosides to improve and repair the function of damaged nerves, and oral α-lipoic acid to nourish the nerves. If patients with diabetic peripheral neuropathy are accompanied by pain symptoms, indomethacin and other drugs can be prescribed to reduce pain. In daily life, patients need to adjust their mentality, pay attention to appropriate exercise, dietary adjustments, etc., to prevent aggravation of the condition. It is recommended that patients with diabetic peripheral neuropathy be treated with medication under the guidance of a physician, rather than using drugs or prescriptions on their own to avoid aggravating their condition.