Avanafil with diabetes can usually be taken. People with diabetes can take Avanafil. Avanafil belongs to the highly selective PDE5 inhibitors, in the body through the phosphodiesterase-5 action occurs, for the fluctuation of blood glucose generally does not have an effect. In addition, there is usually no drug interaction between Avanafil and oral hypoglycemic drugs such as metformin and gliclazide. Therefore, patients with diabetes can generally take Avanafil. Avanafil is mainly used to treat erectile dysfunction in men, and some patients may experience adverse reactions such as headache, flushing, back pain and muscle pain when treated with Avanafil. Diabetic patients need to strictly follow the doctor’s dosage, and should not increase the dosage of the drug arbitrarily, so as not to increase the risk of using the drug. In the process of medication, once serious or progressive discomfort occurs, should promptly consult a doctor, if necessary, by the doctor for appropriate treatment. Combining Avanafil with nitrates may cause low blood pressure, dizziness, fainting, heart attack, etc. Avanafil is not recommended if diabetes is combined with other diseases, such as coronary heart disease. Avanafil is a prescription drug, patients should be used under the guidance of a doctor, and should inform the doctor of the underlying disease, medication history, etc. when visiting the doctor to rule out contraindications to the use of the drug.