The reason why primary premature ejaculation is difficult to treat may be related to its unknown etiology, the lack of highly effective treatment methods and the current poor environment for sex education. 1. The cause of the disease is not clear: primary refers to the cause of the disease is not clear, the traditional view is that most of the psychological factors, in recent years, research has found that genitourinary diseases can also be triggered, but it is not yet clear, so it can not be realized for the cause of the treatment, so it is difficult to cure. 2. There is no highly effective treatment: up to now, there is no drug approved by the State Drug Administration, and now the commonly used drugs are antidepressants, surface anesthetics and PDE5 inhibitors, such as Dapoxetine, lidocaine gel, etc., but each has its own limitations, and can not achieve a better therapeutic effect, and therefore difficult to cure. 3. Poor sex education environment: psychological guidance and behavioral therapy is the main means of treatment, but due to the lack of sex education and exclusion at this stage, it is difficult to achieve the training of sex therapy techniques, or difficult to achieve the desired therapeutic effect, so it is difficult to cure. Primary premature ejaculation is difficult to treat, but can be improved through human intervention, so if there is premature ejaculation related distress, should be timely to the hospital for standardized treatment.