Diabetic patients with blistered skin need to be flushed immediately with cool running water and seek medical attention as soon as possible, with medication if necessary. Skin blisters usually belong to second-degree burns, if the damage to the superficial dermis and dermal papillae. Manifestation of severe pain, sensory hypersensitivity, blister formation, thin-walled, basal flushing or red and white, obvious edema, for shallow Ⅱ degree burns. You can immediately flow cool water rinse, so that the wound is sufficiently cooled down to reduce secondary damage, and at the same time, the external use of silver sulfadiazine ointment and other scalding cream to prevent secondary infection. If the damage reaches the deep dermis, may or may not have blisters, tear off the epidermis to see the base of the wet, pale, edema obvious, dull pain, for the deep Ⅱ degree burns, the need for timely medical treatment, if necessary, implantation of skin treatment. It is recommended that diabetic patients with blistered and broken skin should go to the dermatology department of regular hospitals in a timely manner to complete the relevant examinations and standardize the treatment under the guidance of the doctor, so as to avoid delaying the condition or leading to adverse reactions.