There are many reasons for chest tightness and shortness of breath after waking up in the morning, roughly including physiological factors such as poor sleep at night, but also includes pulmonary embolism, angina or myocardial infarction, bronchial asthma and other disease factors, specifically summarized below. 1. Physiological factors When poor night sleep, late night, overwork and other physiological factors, chest tightness and shortness of breath after waking up in the morning, but through improving sleep, rest can relieve the symptoms, usually do not need special treatment. 2. Pathological factors (1). Pulmonary embolism Shortness of breath after waking up in the morning can be seen in pulmonary embolism, which is often caused by deep vein thrombus dislodgement, and will cause chest tightness and shortness of breath, and in severe cases, chest pain, hemoptysis and so on. (2). Angina pectoris or myocardial infarction This disease is often caused by coronary atherosclerotic heart disease, due to coronary artery stenosis, resulting in interruption of coronary blood flow or occlusion, causing myocardial ischemia, ischemia, necrosis, etc., which can occur in the morning after waking up chest tightness and shortness of breath. (3). Bronchial asthma. Due to chronic inflammation of the airway, airway hyperreactivity causes airway spasm, bronchial asthma attack after waking up in the morning can occur in the morning after the chest tightness and shortness of breath and other manifestations. (4). Other disease factors If there are chronic cardiac insufficiency, anemia, uremia and other diseases, the morning after getting up will also chest tightness and shortness of breath. In short, there are many reasons that can cause chest tightness and shortness of breath after waking up in the morning, and it is necessary to consult the hospital as soon as possible to clarify the cause of the disease and treat it early.