Membranous nephropathy includes primary membranous nephropathy as well as secondary membranous nephropathy, and the specific therapeutic drugs need to depend on the type of disease. Therapeutic drugs include renin-angiotensin-aldosterone receptor antagonists (captopril, cloxartan), glucocorticoids (prednisone acetate), immunosuppressants (cyclophosphamide) and so on.
1. Primary membranous nephropathy: If the quantitative urine protein is less than 4g/24h, symptomatic treatment is usually the mainstay, and commonly used drugs include angiotensin-converting enzyme inhibitors such as captopril and enalapril; angiotensin II receptor blockers such as chloretin and valsartan.
If the quantitative urine protein is 4-8g/24h, immunosuppressant treatment can be considered, such as cyclosporine and tacrolimus; if the quantitative urine protein is more than 8g/24h, immunosuppressant treatment is needed, such as prednisone acetate and cyclophosphamide. At the same time, captopril and cloxartan should be added.
2. Secondary membranous nephropathy: It needs to be treated for specific triggers, and common triggers include tumor factors and rheumatic system diseases.
The application of the above drugs have certain risks, should be used in accordance with medical advice, do not self-medication. Membranous nephropathy patients are advised to go to regular hospitals in time and receive standardized treatment under the guidance of physicians.