Patients with diabetic peripheral neuropathy can be treated by controlling blood glucose levels and improving microcirculation. These include oral hypoglycemic drugs, insulin injection, oral methylcobalamin tablets, etc. It is recommended to follow the doctor’s instructions for treatment. 1. Blood glucose control: Active and strict control of high blood glucose and reduction of blood glucose fluctuation are the most important measures to prevent and treat diabetic neuropathy. For diabetic peripheral neuropathy caused by diabetes mellitus after the condition itself is serious, it can be treated with medication mainly for controlling blood glucose, such as metformin, insulin and so on. 2. Nerve repair: commonly used drugs are methylcobalamin, nerve growth factor and so on. 3. Improvement of microcirculation: Reduced blood flow to peripheral nerves is an important factor leading to diabetic neuropathy. By dilating blood vessels, improving blood hypercoagulability and microcirculation, and improving blood and oxygen supply to nerve cells, the clinical symptoms of diabetic neuropathy can be effectively improved. Commonly used drugs are prostaglandin E1, beclomethasone sodium, cilostazol, hexacosanol, and so on. It is recommended that patients with diabetic peripheral neuropathy go to the hospital in time and follow the doctor’s instructions for treatment to avoid delay.