Medications used to treat overactive bladder include four main classes of drugs. The first major class of drugs are cholinergic receptor antagonists, such as tolterodine tartrate; the second major class of β3-adrenergic receptor agonists, such as drugs like mirabolone, the third class of antidepressants such as desipramine, and the fourth class of calcium channel blockers such as nifedipine. 1. cholinergic receptor antagonist: tolterodine tartrate, used to treat symptoms such as urinary incontinence, urinary urgency, and urinary frequency caused by bladder irritation; adverse effects may include dry mouth, dyspepsia, and decreased tearing. Use with caution in pregnant women, and temporarily discontinue breastfeeding when taking this medication during lactation. 2. β3-adrenergic receptor agonist: Mirabelone, commonly used in the form of extended-release tablets, is used for the symptomatic treatment of urinary urgency, frequency and incontinence in adult patients with overactive bladder. Adverse reactions may include palpitations and urinary tract infections. Can cause side effects of increased blood pressure, patients with severe hypertension, patients allergic to the product is prohibited. 3. Antidepressants: e.g. Disopyramide, this drug works by relaxing the bladder while contracting the bladder neck muscles, which helps to control urinary leakage and improve bladder control. Adverse effects can cause dry mouth and dizziness. 4. Calcium channel blockers: such as nifedipine, etc. Facial flushing is common in first-time users, followed by adverse reactions such as palpitations, and is contraindicated in patients with low blood pressure. Patients with overactive bladder should take medication under the guidance of a physician’s interview, and patients should not use medication on their own to avoid adverse results.