Positive blood urease suggests the possible presence of Helicobacter pylori infection. H. pylori is a gram-negative bacillus that can secrete peroxide dismutase and catalase when it reaches the mucosa of the digestive tract so that it is not killed by neutrophils, and H. pylori is rich in urease, which hydrolyzes urea and produces ammonia to prevent the killing effect of gastric acid. Urease is a metabolite of H. pylori. When blood urease is drawn positive, it suggests that H. pylori infection may be present, which may be secondary to chronic inflammation of the digestive system, and in severe cases, may lead to cancer. If the patient’s blood urease is positive, it is recommended to improve the gastroscopy examination, etc., to clarify the condition and then carry out treatment, so as not to delay the condition.