The treatments for true erythrocytosis include venous bloodletting, prevention of thrombosis, hypocellular therapy, and JAK2 inhibitors.
1. Intravenous bloodletting: 200-400 ml of bloodletting every 2-3 days until the hematocrit (i.e., the percentage of volume occupied by blood cells in whole blood) is <0.45. It should be noted that repeated bloodletting may aggravate iron deficiency. After bloodletting in the elderly, there is a possibility of inducing thrombosis.
2. Prevention of thrombosis: oral small-dose aspirin for long-term prophylaxis.
3. Hypocellular therapy: for age >40 years old, hydroxyurea can be used, for age <40 years old or pregnant patients, interferon therapy should be used.
4. JAK2 inhibitors: such as ruxolitinib, can be used for patients who do not respond to or are intolerant to hydroxyurea.
All of the above drugs should be used under the guidance of a doctor, patients should not self-medication, should go to the hospital in a timely manner, under the guidance of the doctor standardized treatment.