Itchy calves may be a normal manifestation of mosquito bites, or it may be a manifestation of skin allergies, kidney disease, varicose veins of the lower extremities and other diseases. 1. Normal situation: such as not paying attention to personal hygiene, mosquito bites, can also lead to itchy legs. It is recommended to take a shower regularly. 2. Skin allergy: for example, when contacting allergens such as pollen, fur, etc. or being in a humid environment for a long time, it can lead to the appearance of red spots on the skin of the whole body (e.g., around the eyes, face, hands, legs, etc.), accompanied by repeated itching symptoms. 2. Kidney disease: Kidney is one of the important organs for detoxification. When suffering from kidney disease, it can lead to the accumulation of toxic substances, thus affecting the normal metabolic function of the body. When toxic substances or wastes accumulate, they can irritate the skin and cause itching symptoms. 3. Varicose veins of the lower limbs: When varicose veins of the lower limbs, the pressure of vascular reflux in the calf skin increases, which leads to stagnant dermatitis in the calf skin and itchy calf symptoms. If the symptoms of itchy calves appear, you should pay attention to local hygiene and avoid scratching with your hands so as not to aggravate the symptoms. At the same time, it is best to go to the hospital to exclude other causes, targeted treatment.