Frequent premature heart beats are best treated with medications and radiofrequency ablation procedures depending on the number of premature beats. Frequent premature heart beats are categorized into frequent atrial and ventricular premature beats, and atrioventricular junctional premature beats. Frequent premature beats are defined as more than 5 premature beats per minute or more than 500 premature beats on a 24-hour ambulatory electrocardiogram. If the number of premature beats is less than 10,000 or less in a 24-hour period, beta-blockers, metoprolol tartrate, metoprolol succinate, and bisoprolol can be taken. If treatment is not effective, the antiarrhythmic drugs amiodarone and propafenone hydrochloride can be used. Propafenone hydrochloride has the potential to induce heart failure and should be used with caution if there is pre-existing cardiac insufficiency and in elderly patients. If the number of premature beats is greater than 10,000 or more in 24 hours, radiofrequency ablation can be used. If you don’t want to take radiofrequency ablation, you can also take the anti-arrhythmic drugs amiodarone and propafenone hydrochloride orally. It is important to monitor the heart rate while taking the medication, as many medications for premature beats have the effect of lowering the heart rate. If the heart rate is less than 60 beats per minute, go to the hospital in time to adjust the medication as prescribed.