Diabetic nephropathy with creatinine 230μmol/L, if it is a chronic progressive progression, basically has been unable to return to normal, can be treated accordingly to slow down its progression; if it is an acute progression, such as the combination of infections, shock, urinary obstruction and other reasons, creatinine can be further reduced, or even return to normal, after anti-infection, improving effective blood volume, and relieving obstruction.
Diabetic nephropathy is one of the complications of diabetes mellitus. Long-term hyperglycemic state leads to enhanced renal glucose metabolism, altered renal hemodynamics, etc., which ultimately leads to damage in the kidneys and elevated creatinine. The pathological changes of diabetic nephropathy are glomerular hypertrophy, thickening of glomerular basement membrane, widening of the tethered zone, and advanced development of glomerulosclerosis, and this pathological process is irreversible.
When renal function is damaged, chronic damage, creatinine reaches 230 μmol/L, has reached diabetic nephropathy stage 5, treatment can not restore renal function, the pathological changes in the kidney can not be reversed, only through the appropriate treatment, to slow down the further progression of the disease.
When the renal function is impaired by acute injury, such as the combination of infection, shock, urinary tract obstruction and other factors, blood creatinine can be elevated, at this time, through active anti-infection, improve the effective circulating blood volume, release the obstruction, the creatinine may be reduced, or even return to normal.
For diabetic nephropathy patients, it is recommended to consult regular hospitals, under the guidance of professional doctors, reasonable and standardized treatment.