The incidence of chronic prostatitis (CP), which occurs mainly in adult men, is one of the most common diseases in urology clinics, accounting for 25-30% of male urological patients in urban hospitals in China, and the incidence has been on the rise in recent years. It is now widely believed that chronic prostatitis is not a simple disease, but a syndrome that is characterized by abnormal urination and chronic pelvic pain, often complicated by posterior urethritis, vesiculitis or epididymitis, or accompanied by sexual dysfunction and psychoneurological symptoms. The most recent research is briefly described as follows: 1. 1.1 Prostate long-term congestion factors There is a rich venous plexus between the inner and outer peritoneum of the prostate, long-term physical injury and adverse stimuli such as irregular sex, erection without ejaculation, interrupted intercourse or long-distance cycling, prolonged sitting work, will cause damage to the prostate, congestion, bleeding, edema and even necrosis, so that the local resistance to infection is reduced, easily induced 1.2 Pathogenic infection Chronic bacterial prostatitis is caused by bacterial infection, the causative organisms are Escherichia coli, Proteus, Klebsiella, Staphylococcus or Streptococcus, etc. It can also be caused by gonococcal infection, which is mainly retrograde infection through the urethra. Although routine bacterial culture of prostate massage fluid is negative in patients with chronic non-bacterial prostatitis and prostatodynia, it is still believed that a significant number of patients are caused by Chlamydia trachomatis, Mycoplasma, Trichomonas, fungi, anaerobic bacteria, etc. 1.3 Chemical irritation in the urine Because the glandular ducts in the peripheral area of the prostate are thick and lateral to the direction of urinary flow, even at right angles to the urethra, this anatomical feature is the basis for the occurrence of urinary reflux. This is because the prostate gland is a very important part of the body. The actual fact is that you can find a lot of people who are not able to get a lot of money for the purpose of the actual money. The prostate-specific antigen (PSA) and acid phosphatase (PAP) secreted by the prostate gland stimulate the body to produce antibodies, resulting in a series of immune reactions. The results showed that the levels of IgA and IgG were significantly higher than those of the control group, suggesting that the development of chronic prostatitis in humans is most likely related to immune dysfunction. (1) Pain: there may be a burning sensation in the posterior urethra, an anthrax sensation, pain in the perineum and anus may radiate to the lumbosacral area, groin, suprapubic area, penis, testes, etc. Occasionally, it may radiate to the abdomen. (2) urinary symptoms: inflammation involving the urethra, the patient may have mild urinary frequency, urinary urgency, painful urination, individual patients may also appear terminal hematuria, early in the morning before urination or during the bowel movement can be discharged mucus or purulent discharge from the urethra. (3) Sexual dysfunction: there may be loss of libido, impotence, premature ejaculation, painful ejaculation, increased seminal emission, etc. Individual patients may have hematospermia or sperm motility may be reduced due to inflammation of the vas deferens, resulting in infertility. (4) Neurological symptoms: due to the lack of proper understanding of the disease or the patient’s prolonged treatment, there may be depression, fatigue, insomnia, etc. (5) secondary symptoms: due to bacterial toxin-induced metaplasia, conjunctivitis, iritis, arthritis, neuritis, etc. 2.2 Prostate fluid examination Normal prostate fluid (EPS) contains a large number of lecithin vesicles and less than 10 leukocytes/Hp. In patients with chronic prostatitis, the EPS has >10 leukocytes/Hp and fewer lecithin vesicles (less than 50% or very few per high-powered field of view). 2.3 Bacteriological examination The urine four-cup localized bacterial culture test is considered to be the gold standard for definitive diagnosis, that is, the collection of primary urine (vb1) 5-10mL, middle urine (vb2) 20-30mL, prostatic fluid and prostatic fluid after the primary urine (vb3), four specimens were quantitatively cultured for bacteria, compare their results, if prostatic fluid and vb3 are significantly more than vb1 and vb2, can be diagnosed The results were compared, if the prostatic fluid and vb3 were significantly more than vb1 and vb2, the diagnosis of chronic bacterial prostatitis could be made. In patients with CP, especially those with chronic non-bacterial prostatitis (CNBP) and prostatic pain (Pdy), there are varying degrees of increased urethral resistance, high maximum urethral closing pressure, decreased maximum urinary flow rate, and increased mean time to urination. The intra-glandular pressure was significantly higher in the CNBP and Pdy patients compared to the BPH group.