Diabetic nephropathy stage 4 has been 2 years how long can live, usually depends on the condition, treatment effect and so on. The main manifestation of diabetic nephropathy stage 4 is a large amount of proteinuria, up to the degree of nephrotic syndrome, if active control of blood glucose, delay the progression of renal disease, there is no life-threatening, the specific survival time can not be clear. If the blood sugar control is poor, the treatment effect is poor, diabetic nephropathy may soon progress to end-stage renal disease, serious cases can be life-threatening, may affect the life expectancy. Diabetic nephropathy requires low sugar, low fat, high quality and low protein diet, active use of insulin to control blood glucose, so that the blood glucose is controlled at a stable level, and at the same time, under the guidance of the physician, use medications to protect the renal function, such as compound alpha ketoacetic acid tablets, to delay the progression of renal injury. Meanwhile, patients are advised to maintain the psychological state of positive treatment and avoid the psychological burden caused by stress. For patients with diabetic nephropathy stage 4, it is recommended to go to regular hospitals in time and standardize the treatment under the guidance of doctors.