Etiology and pathogenesis of vitiligo

      Vitiligo and its dangers Vitiligo is a relatively common skin disease. This disease is characterized by localized or generalized appearance of white spots on the body, i.e. not elevated or depressed, without exudation or scaling or crusting on the surface. The person suffering from this disease feels nothing, no pain or itch. The essence of vitiligo is due to local or generalized pigment reduction or loss. This is a very good way to get the most out of your life. However, vitiligo in special areas has a greater impact on beauty, such as the face, hands and other exposed areas of vitiligo. Sometimes vitiligo patients may have low self-esteem because of it, and in serious cases, it causes social interaction disorder. For other normal people, it is generally wrong to think that vitiligo is more horrible, or that vitiligo is contagious, and cause incorrect understanding of vitiligo patients. These are incorrect.

The causes and pathogenesis of vitiligo Although vitiligo has harassed humans for thousands of years, but so far we are still not completely clear about the causes of vitiligo. In recent years, through clinical, histopathological, pathophysiological, genetic, biochemical, immunological and other aspects of research, although the accumulation of unsecond information, but can not fully explain the causes of vitiligo and its pathogenesis.

The genetic factors Vitiligo has a genetic background, patients can have a positive family history. The family of vitiligo is 4.9% to 15.6%, which is lower than foreign countries. This is also consistent with the domestic statistics of the prevalence rate is lower than foreign countries. The vitiligo can appear in both of the twins of one egg. Therefore, it has been suggested that this disease may be an autosomal dominant disease with different epizootic rates.